However, the duo of Chris Woakes and Jos Buttler decided to counter attack and stitched a 139-run partnership for the 6th-wicket partnership and led England to a historic fourth-innings chase in Manchester.
The sixth-wicket partnership was finally broken by Yasir Shah when England were just 21 runs away from the target.
Earlier in the day, Pakistan resumed the day on 137-8, with a lead of 244 and managed to add 32 runs to their overnight total, thanks to Yasir Shah's 33-run cameo, which came off just 24 balls.
Stuart Broad and Jofra Archer took the final two wickets to bowl Pakistan out for 169 in their second innings. (UNI)